Melissa Milton enjoys layering many transparent colors on top of one another as a way to suggest new colors and shapes to the viewer.

She paints using conductive paintbrushes and styluses on an electronic touchscreen. Most art pieces are entirely painted whereas others originate from digital photographs she takes and then later paints upon. She oftentimes takes photographs of people underwater because she finds the resultant light effects and shapes to be beautiful. She also enjoys taking photographs of colored liquids unfolding through water, as the effects can vary from serene to explosive.

Melissa prefers digital art for very pragmatic reasons: She is disabled and typically paints lying down. Unlike with wet paint, when one uses digital paint there is no way to spill the liquids. After a digital painting is completed, it is printed out on fine art cotton rag paper, archival quality photo paper, or canvas. Canvases are then stretched onto wooden frames and varnished.

Water is a major influence in Melissa’s artwork because although she can only stand for about five minutes on land, she can stand for hours in the low gravity environment of water. She therefore spends time in water every day. This heavily influences her artwork. It explains a recurring artistic theme of people, animals, or objects gliding about almost weightlessly. A fluidity in the painting style itself frequently appears in her artwork.